Neurological Emergencies

Penetrating Craniocerebral Injuries: Clinical and Radiographic Indicators of Survival.

He S, Pham MH, Zada G, Marquez Y, Giannotta SL

61 Congress of Neurological Surgeons Meeting, Washington DC: October 2011

Read the Full Paper

Key Findings

Take home 1

C5 deficient mice demonstrate decreased white matter ischemia in the corpus callosum

Take home 2

C5 complement protein may play a critical role in mediating white matter injury

Take home 3

C5 may mediate inflammation in the setting of chronic cerebral hypoperfusion.

Take home 4

Astrocyte and microglial activation within the corpus callosum suggests an inflammatory process

Collaborate with Significance Lab

Your organization + Ours

Partner with Us
Donate to Significance Lab

Support our work

Join Significance Lab

Great minds work here

Apply Now

This work is part of the Neurological Emergencies

section of Significance Labs

Learn more