Neurological Emergencies

Metalloproteinases in Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage

Mehta V, Russin J, Spirtos A, He S,  Adamczyk P, Amar A, Mack W. Matrix

Neurology Research International, vol. 2013.

Learn More
Read the Full Paper
Read the Full Text

Key Findings

Take home 1

C5 deficient mice demonstrate decreased white matter ischemia in the corpus callosum

Take home 2

C5 complement protein may play a critical role in mediating white matter injury

Take home 3

C5 may mediate inflammation in the setting of chronic cerebral hypoperfusion.

Take home 4

Astrocyte and microglial activation within the corpus callosum suggests an inflammatory process

Collaborate with Significance Lab

Your organization + Ours

Partner with Us
Donate to Significance Lab

Support our work

Donate
Join Significance Lab

Great minds work here

Apply Now

This work is part of the Neurological Emergencies

section of Significance Labs

Learn more